Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. Malaria plaquenil Aralen online shopping Hydroxychloroquine Sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites Plasmodium vivax, ovale, and malariae by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Structure, properties, spectra, suppliers and links for Hydroxychloroquine Sulfate, 747-36-4. AT791 10 µM, E6446 10 µM, Hydroxychloroquine sulfate 40 µM, or chloroquine 40 µM are added to one of the two compartments in pH 5.5 buffer 50 mM NaAce, 15 mM NaCl or pH 7.4 buffer 50 mM KPO 4, 150 mM NaCl, and the plate is incubated at 37°C. The next day, compound concentrations in both chambers are quantitated. HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. Hydroxychloroquine sulfate molecular weight Hydroxychloroquine sulfate - DrugBank, Hydroxychloroquine Sulfate C18H28ClN3O5S ChemSpider Is chloroquine a quinolineHydroxychloroquine manufacturer not goodHydroxychloroquine what is it used for Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor TLR 7/9. Hydroxychloroquine Sulfate Autophagy inhibitor Read.. Hydroxychloroquine sulfate HCQ sulfate Parasite Inhibitor.. Hydroxychloroquine Sulfate CAS 747-36-4 SCBT - Santa Cruz.. Compound Hydroxychloroquine sulfate with free spectra 1 NMR, 1 FTIR, and 1 Raman. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Please note that the molecular weight for this compound is batch-specific due to variable water content. Packaging Packaged under inert gas Warning Toxicity Harmful C Reconstitution Following reconstitution, aliquot and freeze -20°C. Stock solutions are stable for up to 3 months at -20°C.