There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by incidence or effect, said Frederick W. “Rick” Fraunfelder, MD, director of the Registry and associate professor of ophthalmology at Oregon Health & Science University in Portland. What happens if you take hydroxychloroquine withoutfood Hydroxychloroquine instructions Will plaquenil help anemia Purpose of plaquenil in lupus Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. American Academy of Ophthalmology AAO 2016 guidelines recommend to use HCQ at dosages ≤5 mg/kg real body weight to minimize toxicity 1. Important risk factors for retinal toxicity are daily and cumulative dosage of HCQ, duration of treatment, patient age and concomitant renal or liver diseases 1. Plaquenil Guidelines Point Out New Risks, New Presentation Written By Jean Shaw, Senior Editor, interviewing Rebekah A. Braslow, MD, Sang Jin Kim, MD, and Michael F. Marmor, MD Add to My To-Do List “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. “Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. Aao 2016 plaquenil guidelines My Take on New Ocular Screening Guidelines for Plaquenil., Compliance with Hydroxychloroquine Dosage According to. Chloroquine peak plasma concentrations AAO Screening Guidelines for Plaquenil by S P Check out my recent review/summary of the American Academy of Ophthalmology’s statement on the Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision from the Ophthalmology Journal 2016;186-1394. AAO Screening Guidelines for Plaquenil. Plaquenil Guidelines Point Out New Risks, New Presentation.. Recommendations on Screening for Chloroquine and.. The revised screening guidelines recently released by the AAO are a bit more rigorous than those previously advocated, as they call for the use of newer, potentially more sensitive imaging modalities. By following these guidelines, and by maintaining a high index of suspicion, most cases of severe toxicity may be prevented. What are the current AAO guidelines for monitoring? The AAO revised its guidelines on screening for antimalarial toxicity in 2011 and again in March 2016. Following a baseline examination, annual screening should begin after 5 years of use, when toxicity starts to become more common. Screening guidelines were updated this year, with some pertinent changes for our profession to note. Cumulative dose is no longer a risk factor, but more of a tool in the screening of our patients.