It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil & hrt Chloroquine proguanil At the 2018 ACR/ARHP Annual Meeting, I had the opportunity to co-moderate this year's Great Debate, which was titled "Guidelines for SLE HCQ Dose Should Be No More Than 5 mg/kg In All Patients." Dr. Nathalie Costedoat-Chalumeau of the Cochin Hospital in Paris began the symposium by briefly discussing the risks and benefits of hydroxychloroquine HCQ, and her own work on the use of hydroxychloroquine blood levels. Use For the treatment of acute attacks of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum. Usual Adult Dose for Systemic Lupus Erythematosus. Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response CHICAGO – The dosage of hydroxychloroquine HCQ for treating patients with systemic lupus erythematosus SLE is often overly influenced by fear that the drug could cause blindness, Michelle A. Petri, MD, said at the annual meeting of the American College of Rheumatology. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Dose of hydroxychloroquine for ther treatment of sle Plaquenil hydroxychloroquine sulfate dosing, indications., Hydroxychloroquine Dosage Guide with Precautions - Purpose of hydroxychloroquine Physicians prescribe hydroxychloroquine to treat systemic lupus erythematosus SLE, and it has been shown to have anti-thrombotic effects in SLE patients. Although obvious reasons exist to believe hydroxychloroquine may be useful to treat APS, its use in APS patients remains controversial. Is Hydroxychloroquine Helpful for Patients with.. Fear of blindness hobbles hydroxychloroquine treatment of SLE. Rheumatologists Debate Hydroxychloroquine Dosing.. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Chemoprophylaxis Infants, Children, and Adolescents Oral 6.5 mg/kg hydroxychloroquine sulfate once weekly on the same day each week; maximum dose 400 mg/dose hydroxychloroquine sulfate; begin 1 to 2 weeks before exposure; continue for at least 4 weeks after leaving endemic area CDC 2016. If the initiation of chemoprophylaxis is delayed ie, 2 weeks of therapy not completed prior to the exposure, the manufacturer recommends initiating therapy by doubling the initial dose 13 mg/kg of. Hydroxychloroquine oral tablet is used for short-term treatment of malaria, but it may be used for long-term treatment of lupus or rheumatoid arthritis. Hydroxychloroquine comes with risks if you.