I am currently taking 200mg one time a day and my appetite has seriously decreased in the last two weeks. Just curious if anyone else had this as a side effect. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. I was not losing weight or have a lack of appetite prior to Plaquenil so it must be the medicine. I personally had terrible nausea for almost 2 years when I was put on plaquinel, the nausea was the first symptom to leave....causing me to gain weight. I just find Im not as hungry as I was before, or that my appetite has changed. Chloroquine flatworms Plaquenil flying saucer Gabapentin interactions with plaquenil Chloroquine and primaquine malaria Plaquenil can rarely cause hair loss, but it is not common. be sure to check with your physician and ideally your dermatologist as well to review all possible causes of your hair loss. Jeff Donovan MD PhD FRCPC FAAD US & Canadian board-certified Dermatologist Toronto, Canada Oct 12, 2016 In multivariable models, more weight loss and a greater risk of weight loss odds ratio 1.73 were evident among those receiving leflunomide compared to those receiving methotrexate. Treatment with prednisone was associated with greater weight gain—an average of 0.072 kg/m2. Some contraceptives have been shown to cause weight gain, and Dr. Agarwal says the birth control shot Depo-Provera is chief among them. “Thanks to the dose of the hormone progesterone, it can increase appetite,” she says. Other forms of birth control can also cause weight gain. In this case, the cause of loss f appetite and weight loss has to be found. I was just curious if the medication was what caused my appetite to change or what. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. At my last visit my Dr asked me if it had deminished my appetite so she is aware of it and the amount of weight I lost and is not concerned at this moment. I know diarhea is a common side affect of plaquinel. It wasn't that I was eating a lot, it was just that I was actually eating. I was on Prednisone for two months prior to Plaquenil and gained 18 lbs, so I needed to lose the weight anyway. Does plaquenil cause weight gain or weight loss Hydroxychloroquine and weight gain - Answers on HealthTap, Which Drugs Cause Weight Gain, Loss in RA? - U. S. Medicine Weight gain while using plaquenilChloroquine and prime Taking Prilosec does not necessarily cause weight loss. If you suddenly lose weight, stop taking this medication and contact your doctor immediately. Weight gain is more likely to occur than weight loss attributed to Prilosec. Still, it is rare that this medication causes any weight changes. Prilosec & Weight Loss. Medications That Can Cause Weight Gain. - Prevention. Rx Side Effects New Plaquenil Guidelines and More.. Plaquenil has certainly NOT caused me to lose weight. nI am heavier than I have ever been - and I eat way less than I used to. Hope you get the answers you need. Take care - Scottie Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil is the newest & safest in the class. The drug helps with skin rashes, hair loss, mouth ulcers, joint pain & swelling, fatigue, etc. It takes perhaps 3-4 months to build up & reach full effect. GOOD NEWS hair loss & weight gain are NOT associated with Plaquenil.