Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Hydroxychloroquine plaquenil mechanism of action Is chloroquine related to malarone The risk is much higher in patients who have been taking the drug for 20 years or more. In these patients between 20 and 50 out of 100 will develop retinopathy. At this appointment, a number of photographs and scans will be taken of your retina to assess your eye health and your suitability for screening. Well, that nov post here recommended a visual field test every 6 months, and a computerised 3d retina scan every year - She said she had been on plaquenil for 12 years, regularly having these tests inc I guess doing her amsler grids and she felt they were really important, but so far she had no eye problems. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil eye exam how often My Take on New Ocular Screening Guidelines for Plaquenil., Plaquenil/Hydroxychloroquine - which eye tests do. - LUPUS UK Aralen pastilla In the absence of major risk factors, screening can be postponed for 5 years. Toxicity develops slowly and a yearly exam after year 5 is sufficient. Earlier screening is recommended for patients with any of the previously mentioned risk factors. Annual screening examinations include biomicroscopy. Hydroxychloroquine Plaquenil Toxicity and.. New Plaquenil Guidelines. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. May 12, 2016 Plaquenil Eye Exams. Plaquenil, also known as hydroxychloroquine, is a medication used in the treatment or prevention of malaria. It has also been used to treat other conditions, such as liver disease, that may have been caused by the same parasites that cause malaria. Plaquenil has also been used to treat the symptoms of arthritis. Retinopathy can lead to sight loss so it’s important that you keep your doctor informed of any changes you experience in your vision. If you are using Plaquenil, The Wellish Vision Institute recommends regular eye exams to help catch any change that may be subtly occurring. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Risk of Toxicity The risk of toxicity is dependent on daily dose and duration of use. At recommended doses, the risk of toxicity up to 5 years is under 1% and up to 10 years is under 2%.