Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Hydroxychloroquine brand Malaria treatment chloroquine how many daily Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in. The drug is known as chloroquine, and although traditionally an off-label malaria drug, its recent success in stabilizing brain tumors suggests it may have a future in oncology. The patient, Lisa Rosendahl, was given only 12 months to live after her brain tumor proved unresponsive to all known treatments. Anti-malaria Drug Chloroquine May Help Combat Some Brain Tumors Investigators at the University of Colorado are now reporting that adding the anti- malaria drug chloroquine to standard therapies. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Glioblastoma chloroquine Chloroquine for Glioblastoma Multiforme Annals of Internal., Glioblastoma Treatment Breakthrough 'Untreatable' Brain. Hydroxychloroquine sulfate tabsPlaquenil weight gain at 400mgChloroquine toxicity heartPlaquenil and knee replacement In this critical review, Katharina Seystahl and colleagues summarise the available literature for patients with recurrent progressive glioblastoma treated with repeat surgery, re-irradiation, chemotherapy or immunotherapy approaches. This is an abridged version of K Seystahl et al 2016 Therapeutic options in recurrent glioblastoma –an update. Therapeutic options in recurrent glioblastoma – an update.. Anti-malaria Drug Chloroquine May Help Combat Some Brain.. Re-purposing Chloroquine for Glioblastoma Potential.. Glioblastoma is one of the most aggressive human cancers shown to have a better response to standard therapy when combined with chloroquine. While there is considerable evidence for the efficacy and safety of chloroquine as an adjuvant treatment for cancer, the mechanisms underlying the tumor suppressive actions of this drug remain elusive. Chloroquine as Adjuvant to the Treatment of Glioblastoma Multiforme, A Randomized Trial Brief Summary Chloroquine is a strong lysosomotropic and DNA-intercalating agent in experimental studies This project is supported by the Canadian Institutes of Health Research award #111062, Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre TMIC, a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization.