Been waiting for a rheumatology appointment for 13 weeks so far which is giving me too much time to think!! After 3 years of joint pain and fatigue and constantly getting a negative rheumatoid factor blood test result, on my last big flare up in Feb the bloods came back as positive for rheumatoid factor with my GP. Hydroxychloroquine nursing implications Hydroxychloroquine sulfate and pregnancy I was on plaquenil for years with a diagnosis of UCTD; in 2017 I was upgraded to RA and started on sulfazaline and more recently MTX. When I was diagnosed with UCTD, I had a positive rheumatoid factor but not enough other symptoms to be diagnosed specifically with RA. Rheumatoid arthritis is the most commonly diagnosed systemic inflammatory arthritis. Women, smokers, and those with a family history of the disease are most often affected. Criteria for diagnosis include having at least one joint with definite swelling that is not explained by another disease. May 24, 2011 Plaquenil worked wonderfully well for six months. It did take a while to kick in. After six months, I developed a sore tongue, and then red sore bumps on my tongue, so I was taken off if Plaquenil immediately. I have just started MTX. I hope Plaquenil owrks for you. I felt so well when I was taking that drug. I am worried that when the appointment for the consultant finally comes through my rheumatoid factor will be negative again? Although certain joints are now permanently painful most swelling has gone down. Rheumatoid factor dropped plaquenil Plaquenil -, Diagnosis and Management of Rheumatoid Arthritis. Plaquenil and allergy testing Dec 21, 2015 They’re names of blood tests used in diagnosing and managing rheumatoid arthritis. When you’re new to this disease, they can seem as mysterious and impenetrable as a secret language. What do. Rheumatoid Arthritis Blood Tests – What Do They Mean.. Plaquenil for RA -. Taking Plaquenil for Rheumatoid Arthritis. I still have flares now and then, but work full time. I have not had problematic side effects from the Plaquenil or MTX, but the steroids caused weight gain and some hair loss besides what was caused by the arthritis. I am still negative for the RA factor, but have suffered with bilateral trochanteric bursitis and pain at the sides of my knees. I have all the clinical symptoms of Sjögren's, but only a slightly elevated ANA. I have been on Plaquenil just over 2 years with good results. A part of me is always questioning whether I really have this disease or not because my bloodwork doesn't show any SSA, SSB and no rheumatoid factor either. Hydroxychloroquine is considered safe in all trimesters of pregnancy. Due to the high risk of flare in systemic lupus erythematosus when discontinuing this medication, continued Plaquenil use is advised in these patients during pregnancy.