It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine fansidar and mefloquine Hydroxychloroquine hair lightening Women with rheumatic diseases, including inflammatory arthritis and systemic lupus erythematosus SLE, fare better in pregnancy when their disease is under good control1,2. The role of hydroxychloroquine HCQ for achieving this control is now recognized. Several studies demonstrate that patients with SLE who continue HCQ during pregnancy have decreased flares and improved pregnancy outcomes. As these have proved safe and efficacious in pregnancy 5. Hydroxychloroquine in particular is associated with improved obstetric outcomes in SLE 9. Chloroquine, although grouped with hydroxychloroquine in table 2 of this article, is not routinely used in the management of SLE either in or out of pregnancy due to increased tissue Answer Pregnant women should avoid travel to malaria-endemic areas if possible. However, if travel cannot be avoided, measures to prevent mosquito bites, along with an effective chemoprophylaxis regimen, should be implemented. Chloroquine or hydroxychloroquine are considered safe to use in all trimesters of pregnancy. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Chloroquine pregnancy category Lupus and Pregnancy Tips for Living with Lupus While Pregnant, Treatment of SLE in pregnancy and use of Chloroquine The BMJ Can you take turmeric with hydroxychloroquineDoes chantex react to plaquenilCan plaquenil and elavil be taken togetherTreatment for chloroquine resistant vivax malariaPlaquenil withdrawal Nov 25, 2019 Chloroquine has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm. Chloroquine Use During Pregnancy. Prophylactic use of antimalarials during pregnancy. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Previously mefloquine was not recommended for the treatment of malaria in pregnant women. The change in recommendations is based on the recent Food and Drug Administration FDA re-categorization of mefloquine from a pregnancy category C drug to category B, based on their review of the published data on mefloquine use during pregnancy. Use in pregnancy There is no evidence that chloroquine is harmful in prophylactic doses during pregnancy. Because of the susceptibility of pregnant women to falciparum malaria, it should be used at the recommended dosage for both prophylaxis and treatment wherever chloroquine-sensitive malaria is prevalent. May 13, 2009 OR of congenital defects and live births. Other studies have reported that HCQ is safe to use during pregnancy but had no control group 35–40. All 4 of the studies 27–30 assessed the presence of congenital defects in babies born to women with autoimmune diseases Additional file 1, Table S2 and Figure 2a.