While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Cost for hydroxychloroquine Plaquenil and acne How do I control the itchiness of the rash? I was diagnosed a week ago with lupus, & have been on the plaquenil since then too. Today I called the clinic that I use, & left a question for my doctor, for them to ask if I needed to increase my dose, needed something else, or just wait it out, & give it more time to work. I had been taking plaquenil since April for my lupus and sjogrens. It was working really well and just recently my rheumy told that I was in remission. I felt great. Then I had an allergic reaction to the plaquenil - a rash all over my body, neck, arms and legs. I stopped taking it 1 week ago. It does not appear to be from the Plaquenil but, simply Lupus. Don't mean to scare you but, this can be caused by Plaquenil OR by Lupus OR M. S. Don't wait to have your eyes checked out if you are having any vision issues or the doctor sees an issue. I have been getting these horrible rashes and they are not related to sun exposure. I am interested to see if anyone here has gotten a rash from Plaquenil after being on it for several months. Plaquenil for lupus rash Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Allergic reaction to plaquenil DailyStrength Hydroxychloroquine labs to monitorHydroxychloroquine ncbiHydroxychloroquine and sun exposureIs plaquenil a quinolonePlaquenil c 24-2 The incidence of new-onset or flaring psoriasis associated with Plaquenil varies from 0-100% depending on which case series report you read! Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Plaquenil Use in Autoimmune Diseases. Immune & Autoimmune - Lupus How long do your malar rashes.. Plaquenil and itching -. Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It has also been found to help in a number of other features of the disease, though less predictably. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight. In 1984, I wrote my first prescription for the antimalarial drug, hydroxychloroquine Plaquenil, for a 28-year-old woman with SLE. She was considerably overweight, with inflammatory arthritis and a photosensitive rash, and I worried that oral corticosteroids would tip her over into diabetes. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. What Drugs, Substances, or Supplements Interact with Plaquenil?