Keep in mind that most people with Sjogren's stay healthy and don't have serious problems. You should be able to keep doing all the things you love to do without making many changes. Hydroxychloroquine loss of appetite Plaquenil arthritis treatment Plaquenil for alopecia areata Long term effects of plaquenil sulfate In some patients, the anti-rheumatic drug Plaquenil has been beneficial in decreasing pain and salivary gland swelling. Sjogren's Syndrome Foundation. MedlinePlus "Sjogren's Syndrome." Hydroxychloroquine is safe, even for pregnant women with Sjogren's syndrome. Rarely, it can accumulate in the retina, the tissue at the back of the eye that helps. Hydroxychloroquine generic Plaquenil is often prescribed off-label by doctors for Sjogren’s Syndrome patients despite the fact that it has never been approved by governing agencies like the FDA. I myself have taken hydroxychloroquine for several years. Conditions like this are called autoimmune diseases. Sjogren's causes your immune system to go haywire and attack healthy cells instead of invading bacteria or viruses. Plaquenil for sjogren's syndrome Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic, Medications for Sjogren's Syndrome NYU Langone Health How does hydroxychloroquine work for arthritis Sjögren's syndrome SS is a complex chronic autoimmune disease characterized by a wide spectrum of clinical manifestations. Lymphocytic. Is hydroxychloroquine effective in treating primary Sjogren's.. Plaquenil/hydroxychloroquine may have more extraglandular.. Plaquenil for treating Sjogren's Syndrome Treato. The two main symptoms of Sjogren's syndrome are Dry eyes. Your eyes might burn, itch or feel gritty — as if there's sand in them. Dry mouth. Your mouth might feel like it's full of cotton, making it difficult to swallow or speak. Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. Rarely, it can accumulate in the retina, the tissue at the back of the eye that helps to create images to be processed by the brain. Deposits on the retina can lead to vision changes. If you’re taking hydroxychloroquine. There are other treatments for some of the less common symptoms of Sjogren's syndrome. For instance, if you get yeast infections in your mouth, your doctor might prescribe anti-fungal medicine. If you get heartburn, your doctor may give you medicines that curb the amount of acid in your stomach.