I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. Plaquenil vasculitis Makers of plaquenil Plaquenil immunosuppressive therapy Chloroquine atovaquone Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Note that chloroquine is not used frequently in the United States and has been replaced by the use of hydroxychloroquine because the latter has fewer side effects. The Plaquenil Problem “Plaquenil toxicity is very distinctive,” said Michael F. Marmor, MD, professor of ophthalmology at Stanford University. Dr. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. For the four years that I took the drug, my eye sight never bothered me and bi-annual eye tests revealed no changes. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially tests need to be done every six months. Side effects of discontinuing plaquenil Side effects to Stopping Plaquenil. - Sarcoidosis - Inspire, Rx Side Effects New Plaquenil Guidelines and More - American Academy. Warfarin interaction with hydroxychloroquin Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Summary Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. What Are The Side Effects Of Stopping Methotrexate? I have been on Methotrexate for three months. I have become so exhausted and weak, that everyday activities are much more difficult.