It seems to me the cure is worse then the condition! Hi im starting plaquenil 200mg twice a day was wondering how far apart should the dose, be and best times to take it ,what are some of the side effects anyone has had and how long did it take to start working thank u You take plaquenil twice a day, approximately 12 hours apart. Hydroxychloroquine hair bleaching Plaquenil side effects insomnia When I was on plaquenil twice a day my dr has reduced it now says I was taking too much for my weight, really. I would take one in the morning with breakfast and one at night after supper. It bothers my stomach so I find it is best to take it with food. Hi I was told to wean my self onto Plaquenil slowly with only half a tablet every other day to begin with and to always take it with food. It took me about a month to get onto a dose of 200mg a day. 200 didn't seem to make much difference so I was told to 'up it' to 400mg a day and it took me another month to taper up to that. I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. I take my plaquenil with my evening meal. When is the best time to take it? Would it be best in the morning? I also take in the morning thyroxine, omeprazole and co-codamol, would it interfere with any of those if I took it in the morning instead of. You can take it with food if it upsets your stomach. The most common side effect is mild nausea and occasional stomach cramps. Best way to take plaquenil Best time to take plaquenil - HealthBoards, How do you take Plaquenil? - Sjogren's World Is there a natural drug substitute for plaquenilPlaquenil 200 mg precioStopping plaquenil for surgeryPlaquenil eye exam protocol Hello friends, I take my Plaquenil in the morning with breakfast. I feel very shaky, dizzy and just off all day. Does anyone take it at night? Will it keep me up? Why do I have to take it in the morning. Can I take Plaquenil at night? - Sarcoidosis - Inspire. When best time of day to take plaquenil? - LUPUS UK. Plaquenil Uses, Dosage & Side Effects -. Plaquenil is a slow acting drug and most people dont notice any difference in the way they feel for at least a month. It takes up to 3 months to build up in your body and actually start to make a difference in your blood work and symptoms. Most rheumy's will give plaquenil along with prednisone to boost/quicken the anti-inflamitory process. Of all the drugs I've had to take for lupus, plaquenil is probably the most mellow. It is my understanding that if it affects your eyes, it's a slow onset type thing, so if you're having your eyes checked regularly every 6mos, you will be fine. Hi Guys, I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good I s'pose but I drop nearly every afternoon.