My skin turns red, and it feels like something is biting me. It's bad around my ankles and the tops of my feet, my arms, and I get red blotches and spots on my chest. Chloroquine dreams Hydroxychloroquine sul 200 Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Effects of chloroquine? Chloroquine is a relatively well-tolerated. medicine. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking chloroquine with food. Chloroquine may also cause itching in some people. All medicines may have some side effects. I was wondering if anyone else was experiencing this and what they did to help it! I was reading online and some people had mentioned that the name brand Plaquenil didn't cause such a severe reaction. Itching after taking chloroquine Itchy Skin No Rash Causes, Symptoms, and Treatments, Plaquenil Side Effects Common, Severe, Long Term - Hydroxychloroquine canadaHow effective is plaquenil for scarring alopecia Unbearable itch after withdrawal of antihistamines is not a common phenomenon. A PubMed search revealed no published reports of this association. However, there has been extensive discussion about the occurrence of pruritus after withdrawal of levocetirizine on several patient forums and blogs 5, 6. Unbearable Pruritus After Withdrawal of Levocetirizine. Medicines for the Prevention of Malaria While Traveling.. Chloroquine Side Effects Common, Severe, Long Term -. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Take chloroquine at least 2 hours before or after taking ampicillin. Chloroquine may decrease the amount of ampicillin in your body and the ampicillin may not work as well. Signs of a severe allergic reaction, which may include hives, rash, itching, difficulty breathing, tightness in the chest, or swelling of the face, mouth, lips, or tongue Back to Top Chloroquine.