It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Naprosen and plaquenil Plaquenil pill image Is plaquenil a disease modifying Hydroxychloroquine sulfate monitor Summary Drug interactions are reported among people who take Methylprednisolone and Plaquenil together. This study is created by eHealthMe based on reports of 165 people who take Methylprednisolone and Plaquenil from Food and Drug Administration FDA, and is updated regularly. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and methylprednisolone Plaquenil vs Prednisone for PMR Polymyalgia Rheumatica., Plaquenil Hydroxychloroquine - Side Effects, Dosage. World war 2 and lupus and hydroxychloroquine plaquenilHydroxychloroquine hypokalemiaSynthesis procedure of chloroquinePlaquenil safer than floroquinolones All information contained within the Johns Hopkins Lupus Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. Treating Lupus with Steroids Johns Hopkins Lupus Center. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Rheumatoid Arthritis Treatment Options Johns Hopkins.. The prednisone is a steriod and the plaquenil is a anti malaria drug. The thing with plaquenil for me is that I don't notice much of anything taking it but when I go off then I flare up and then really notice it. I have been taking the plaquinil for about 8 years morning and night and the prednisone off and on. Compare Plaquenil vs Prednisone head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Plaquenil rated 6.8/10 vs Prednisone rated 7.7/10 in overall patient satisfaction. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.