Mixed connective tissue disease (MTCD) is an uncommon systemic inflammatory rheumatic disease. MCTD is a specific subset of the broader category of rheumatic “overlap syndromes”, a term used to describe when a patient has features of more than one classic inflammatory rheumatic disease. Hydroxychloroquine liver How long does it take plaquenil to leave your system Hydroxychloroquine precautions UCTD and Plaquenil. Finally, I have seen another rheumy for a second opionion, and have received the diagnosis of Undifferentiated Connective Tissue Disease UCTD that could develop in to Lupus. My blood work is not yet providing solid evidence for a Lupus diagnosis to be made. I've been on Plaquenil since March 2017 for recent diag of Mixed Connective Tissue Disease. Prior to that 13 yrs of seeing specialists for body aches, total body inflammation/swelling, joint pain, & stiffness - majority in neck/shoulders/entire back. Body aches increased often after eating. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Mixed connective tissue disease and for what kind of people. The study is created by eHealthMe from 35 Plaquenil users and is updated continuously. eHealthMe has been monitoring drugs and supplements since 2008. Individuals with an overlap syndrome may, but need not meet, complete diagnostic criteria for one (or more than one) classic rheumatic disease. These classic rheumatic diseases include systemic lupus erythematosus, polymyositis, scleroderma, and rheumatoid arthritis. Plaquenil and mixed connective tissue disease Undifferentiated connective tissue disease Genetic and Rare., User Reviews for Hydroxychloroquine to treat. - Plaquenil contraindications Apr 27, 2011 Being me, I ignored this mandate for another year and a half I felt fine and finally made my way to a rheumy this past December I am trying to get pregnant and thought I should have this checked out wherein, based on my bloodwork ANA homogenous, RNP 6.8, elevated C-Reactive Protein, I was diagnosed with Mixed Connective Tissue Disease. Plaquenil while asymptomatic? - Connective tissue disorders.. How effective is Plaquenil for Mixed connective tissue.. Mixed Connective Tissue Disease MCTD - Cleveland Clinic. Mixed connective tissue disease is an autoimmune disease with overlapping characteristics of five other connective tissue diseases — systemic lupus erythematosus, scleroderma, polymyositis, rheumatoid arthritis RA, and Sjogren’s syndrome. It is sometimes referred to as an overlap syndrome. May 08, 2017 She says I do not have Lupus were just going to diagnose you with Mixed Connective Tissue Disease for now, take Plaquenil 400mg daily come back in 3 months. That's all! I've lost 15 pounds in a month my hair keeps falling out,my body hurts like hell, my skin is a little better granted I use a steroid cream from the derm. I am on Plaquenil 400 mg daily 1 caplet in the morning and one in the evening. I have had to see where the problem is and what kind. I was diagnosed with the mixed then last week it was undifferentiated connective tissue disease. Along with constrictive bronchiolitis obliteration. So much is going on.