Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil and swollen lymph nodes Hydroxychloroquine and neutropenia Hypotension predictably follows intravenous injection of chloroquine and is associated with transiently very high blood levels Looareesuwan et al. 1986. Chloroquine is also rapidly absorbed following intramuscular or subcutaneous injection even in seriously ill patients White et al. 1987b. Parenteral chloroquine may be administered safely by simply giving smaller, more-frequent doses than are currently used or, in the case of iv administration, by using continuous infusion. PMID 3543146 Chloroquine diphosphate 3 mg base kg-1 was given by constant rate intravenous injection over 10 min to 12 healthy adult male volunteers. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Intravenous chloroquine injection Injections for Malaria Treatment? –, Parenteral chloroquine for treating falciparum malaria. Plaquenil is os junction While timely delivery of IV artesunate is anticipated, healthcare providers should consider treating the patient with an oral treatment while waiting for IV artesunate to arrive. Artemether/lumefantrine Coartem ® is the preferred antimalarial for interim treatment because of its fast onset of action. Intravenous Artesunate for Treatment of Severe Malaria in.. Cardiovascular toxicity and distribution kinetics of.. Single Intravenous Injections of Chloroquine in the Treatment.. Chloroquine Injection is used for malaria, amebiasis, rheumatoid arthritis and other conditions. Oct 01, 2018 Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Aug 19, 2014 Mice injected daily with chloroquine showed slower growth and less lung metastasis of subcutaneous melanoma xenografts. However, chloroquine did not suppress the invasion of cultured cancer cells into Matrigel, and lung colonization was not reduced by exposure of cancer cells to chloroquine prior to intravenous injection in mice.