Treatment of chloroquine resistant malaria in pregnancy

Discussion in 'International Pharmacy' started by spleen, 07-Mar-2020.

  1. Sew New Member

    Treatment of chloroquine resistant malaria in pregnancy


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Despite this in most malaria endemic regions antimalarial treatment of pregnant women remains reliant on quinine, chloroquine or sulfadoxine-pyrimethamine SP based regimens. However the use of these conventional treatments become increasingly compromised by the widespread drug resistance to chloroquine and SP. Intermittent preventive treatment of malaria in pregnancy IPTp with sulphadoxine-pyrimethamine SP reduces the incidence of low birth-weight, pre-term delivery, intrauterine growth-retardation and maternal anaemia. Chloroquine phosphate is a 4-aminoquinolone that acts by inhibiting heme polymerase. 198 Chloroquine is well tolerated and in appropriate doses may be safely used by young children and pregnant women. 199 Transient nausea or vomiting is seen in a small proportion of individuals and may usually be reduced by taking the drug with food.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Treatment of chloroquine resistant malaria in pregnancy

    Guidelines for Treatment of Malaria in the United States., Azithromycin-chloroquine and the intermittent preventive.

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  4. For pregnant women, chloroquine is the preferred treatment for malaria. Quinine, proguanil and clindamycin typically are used for pregnant people with malaria that is resistant to chloroquine. When To Call a Professional

    • Malaria Guide Causes, Symptoms and Treatment Options.
    • Chloroquine - an overview ScienceDirect Topics.
    • Azithromycin-chloroquine and the intermittent.

    Chloroquine CQ resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

     
  5. brtr New Member

    Some people, especially children, recover completely, while others experience greatly diminished symptoms for long periods of time. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic Plaquenil Use in Autoimmune Diseases How effective is Plaquenil for Dermatomyositis by duration.
     
  6. Krema User

    Some medications are available for a fee of for up to a 180 day supply. Plaquenil prices & coupons Optum Perks formerly searchRx Plaquenil Hydroxychloroquine - Per Month Total Cost. Plaquenil Coupon and Discount - Save. Health
     
  7. domipoteki Well-Known Member

    Hydroxychloroquine - Wikipedia Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.

    Hydroxychloroquine Oral Tablet 200Mg Drug Medication.
     
  8. bestmark New Member

    Reasonably Well Plaquenil and Hypoglycemia Mar 07, 2011 So back to the Sjogren's World Forums participant this person noticed that after beginning to take Plaquenil, it became more difficult to keep her diabetes in control occasionally her blood sugar became too low and she had symptoms of hypoglycemia feeling very anxious, tremor, feeling suddenly very hungry, perspiring heavily, and feeling faint. Several others chimed in, many of whom were not diabetic, and said that they noticed the same thing.

    A favorable effect of hydroxychloroquine on glucose and lipid.