PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. What class of medication is plaquenil Chloroquine during pregnancy Chloroquine in early pregnancy Regarding hydroxychloroquine levels and lupus activity, Costedoat- Chalumeau et al 24 measured whole blood levels in 143 individuals taking a standard dose of 400 mg per day and found a lower hydroxychloroquine level in those with active disease and that lower baseline levels were predictive of disease flare. Long term plaquenil users on high doses will need to get check-ups for eye health regularly to prevent retinal toxicity from long-term use. Pregnant women should continue to take their antimalarial medication as prescribed to avoid a lupus flare. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Therapeautic dose of plaquenil for lupus Experts debate hydroxychloroquine dosing guidelines in lupus, Medications used to treat lupus Lupus Foundation of America Herpes and plaquenil Hydroxychloroquine has the benefits of reducing cholesterol levels, a modest anti-platelet effect and it may reduce the extent of permanent tissue injury in lupus. Hydroxychloroquine appears to be safe in pregnancy. The addition of mepacrine 50-100mg daily may be useful in those not responding to hydroxychloroquine alone. Drug Therapy of Lupus - LUPUS UK. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Hydroxychloroquine in systemic lupus erythematosus SLE.. Term or high-dosage 4-aminoquinoline therapy for discoid and systemic lupus erythematosus, or rheumatoid arthritis. Retinopathy has been reported to be dose-related. When prolonged therapy with any Antimalarial compound is contemplated, initial base line and periodic every three months ophthalmologic examinations including visual acuity, Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives.