Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. How to taper off hydroxychloroquine Drug innteraction of adderall with plaquenil Plaquenil genetic risk test Drugs most notable for color vision changes include sildenafil citrate Viagra, digoxin Lanoxin, amiodarone Cordarone, hydroxychloroquine Plaquenil and ethambutol Myambutol 2. Blue Vision These side effects peak within 1 to 2 hours after you take the drug. Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. Also, Plaquenil may have various systemic side effects that are not related to the eyes. These too are rare and include nerve weakness, hallucinations, psoriasis and changes in hair color. The eye complications are the most serious and worrisome. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil and color vision PowerPoint. Update on Plaquenil Testing, PLAQUENIL hydroxychloroquine and the Eye Westford Trental and plaquenil together If you feel like your central vision is getting blurred, if you lose the ability to see a digital clock, if you lose color vision—if reds look kind of washed out—or if you have trouble seeing at night Those are early signs that you might be developing Plaquenil retinopathy,” says Katz. Protecting your eyesight when taking Plaquenil Lupus.. Rx Side Effects New Plaquenil Guidelines and More - American.. Hydroxychloroquine-Induced Retinal Toxicity - American.. A Change In Vision; Acquired Chromatopsia, A Change In Color Vision; Irritability; Loss Of Muscle Coordination; Low Energy; Mood Changes; Muscle Tremors; Muscle Weakness; Nightmares Plaquenil is a drug used in the acute treatment of malaria. If a person is going to be treated long-term with Plaquenil, they need to have a thorough dilated eye exam with best corrected visual acuity, central visual field, color vision, and dilated examination of the retina. Feb 19, 2020 PLAQUENIL tablets are white, to off-white, film coated tablets imprinted “PLAQUENIL” on one face in black ink. Each tablet contains 200 mg hydroxychloroquine sulfate equivalent to 155 mg base. Each tablet contains 200 mg hydroxychloroquine sulfate equivalent to 155 mg base.