I have been getting these horrible rashes and they are not related to sun exposure. I am starting to wonder if they are related to Plaquenil. Plaquenil and cyclosporine Hydroxychloroquine diabetes 2019 Note that adverse cutaneous reactions to hydroxychloroquine are reported to affect more than 30% of patients with dermatomyositis, compared to a lower risk of rash in patients with cutaneous lupus erythematosus. If a rash appears, hydroxychloroquine should be withdrawn and may be restarted at a lower dose. Less common skin side effects may include Plaquenil = Rash? I am on the generic version of Plaquenil and have been for about a month with no side effects. I started the first week with 1 morning dose, then on the second week I am on 2 doses after breakfast and after dinner I haven't had any side effects. Find information about common, infrequent and rare side effects of Plaquenil Oral. I've always been one to go for the natural route and am starting to feel like I should just stop taking everything and see what happens - so frustrating. My doctor now wants me to start on Chloroquine instead of plaquenil. Plaquenil rash side effects Side Effects of Plaquenil Hydroxychloroquine,, Plaquenil = Rash? lupus Plaquenil makes my stomach bleedCan plaquenil cause hypoglycemia Malaria. PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Indications, Side Effects, Warnings -. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or.