Chemical synthesis of chloroquine

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  1. 4MIN New Member

    Chemical synthesis of chloroquine


    Join Britannica's Publishing Partner Program and our community of experts to gain a global audience for your work! Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate.

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    Chloroquine, synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be Chloroquine and its analogs inhibit synthesis of nucleic acids of the parasite by affecting the matrix function of DNA. This happens by preliminary binding of the drug through hydrogen bonds with the purine fragments, and subsequent introduction of the chloroquine molecule between the orderly arranged base pairs into the spirals of the DNA of. A new silver–chloroquine CQ–Ag complex CQAgNO3, CQ = chloroquine, C18H26N3Cl has been synthesized and characterized by using a combination of NMR solution and solid-state, FTIR, molar conductivity and ESI/FT-ICR high resolution mass spectroscopy with DFT calculations.

    Chloroquine is effective against susceptible strains of the malarial parasites , as well as certain parasitic worms and amoebas. It also can be given by intramuscular injection as chloroquine hydrochloride.

    Chemical synthesis of chloroquine

    Organic chemistry - Synthesis of chloroquine from, Chloroquine - an overview ScienceDirect Topics

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    The following article looks at the medicinal chemistry of antimalarial drugs. It will look at – in detail – quinine and quinine-related drugs. In a previous article, we briefly described malaria and artemisinin as a lead compound for new antimalarials. We now turn our attention to the other antimalarial drugs. Search results for Chloroquine at Sigma-Aldrich. Summary This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. That would be the synthesis of chloroquine from 4,7-dichloroquinoline and 4-diethylamino-1-methylbutylamine, where both starting materials are available through well-known procedures.

     
  5. vika New Member

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Chloroform Fun Video Sleeping mode ll #chloroform #strangle #towelhanky. Chloroquine Indications, Side Effects, Warnings - What's the relation between chloroform and chlorophyll.
     
  6. Lenna Moderator

    Plaquenil Hydroxychloroquine - Side Effects, Dosage. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few.

    Hydroxychloroquine MedlinePlus Drug Information
     
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    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.