I saw a GP about it (not my usual one) and they strongly suspect it is being caused by MTX but I have just spoken to the Rheumy nurse who thinks Hydroxy is the more likely suspect or it may be an autoimmune response so now I have to withhold all rheumy meds. It seems to improve when I am on steroids but only at higher doses. Thanks, Tamara I am on all sorts of meds including MTX and Hydroxy. Plaquenil and period changes Plaquenil c 24-2 Plaquenil for chilblains Plaquenil blurry vision reviews Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. A skin rash can be a sign of an allergic reaction to a drug. So you should let your doctor know if your skin breaks out or starts itching. Depending on the type of rash you have and how severe it is, your doctor may lower the dose or stop your medication altogether. Aug 26, 2013 Hair bleaching, hair loss, skin pigmentation, rash and itching are recognized skin adverse reactions of plaquenil hydroxychloroquine. These reactions tend to be worse if a patient is taking other medications that have similar skin toxicity. Please consult a dermatologist to ensure skin lesions are not psoriatic because Plaquenil hydroxychloroquine use needs special precautions in psoriasis. I can't face the GP again, as I am sure I am one of the "heart-sink" patients! I have recently developed an itchy rash which only affects my cheeks and eyebrows and haven't a clue what's causing it, so I hope you get some helpful replies that might help me too! Plaquenil rash and itching Rash from Methotrexate or Hydroxychloroquine? - NRAS, Rheumatoid Arthritis Skin Problems Nodules, Rashes, and More Plaquenil south africaContraindications for plaquenilPlaquenil 2016 Hi, I started taking Plaquenil on June 24th and for the last four or 5 days have had horrible itching. No rash just all over itching. My Rhuemy told me to stop taking it until all itching symptoms were gone, then wait another week and start up again with 1 pill 200mg a day instead of 2 pills. Itching From Plaquenil DailyStrength. Plaquenil hydroxychloroquine 200mg is it causing itchy skin.. Plaquenil and SEVERELY ITCHY SKIN! PLZ HELPPP.. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Has anyone else noticed that plaquenil makes them itch? I've been on it for 10 months and I noticed within a couple of weeks that I was pretty itchy. I recently went to the dermatologist for a rash and he said that my rash was from scratching. I think the itch has become worse since I started on Cymbalta. Does anyone else have this problem?