Additionally, another exception occurred while executing the custom error page for the first exception. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Drug interactions between plaquenil mycophenolate and prednisone How to dissolve chloroquine Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Screening for Plaquenil Toxicity • SD-OCT can show localized thinning of the parafovealretinal layers confirming toxicity – May be unable to see with TD-OCT – Changes maybe visible prior to VF defects • FAF may reveal subtle RPE defects with reduced autofluorescence • MF-ERG can objectively document localized paracentralERG depression. Humphrey Visual Field 10-2 Testing demonstrates a paracentral scotoma which is consistent with this macular toxicity that occurs with Plaquenil This patient was diagnosed with macular toxicity, secondary to plaquenil use. She was educated to discontinue plaquenil and is following up with a retina specialist. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. Plaquenil toxicity vf Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening, Optical Coherence Tomography OCT The Origins of the OCT Difference between primaquine and chloroquine Focus on Eyes Long-term Plaquenil intake can affect your vision. Taking high doses or long-term treatment of Plaquenil, an anti-malaria drug used to treat lupus, can lead to vision problems. Focus on Eyes Long-term Plaquenil intake can affect your vision. Dr. Noskow's Case Report Plaquenil Toxicity - Hollywood Eye Institute. Multimodal Imaging in Plaquenil Toxicity. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine Maculopathy An Update on Screening and Diagnosis A brief guide for imaging SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. In early cases of Plaquenil toxicity, an early indicator of damage is the appearance of a paracentral scotoma seen on automated visual field testing in the absence of fundus changes. 18 Each of the testing strategies can be used to detect early toxicity changes, but the presentation of the visual field effects will vary. Due to the central area.