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    Il componente attivo del farmaco selettivamente reversibile inibisce il guanosina monofosfato ciclico (c GMP) - specifica fosfodiesterasi di tipo 5 (PDE 5). Durante la stimolazione sessuale viene marcato il rilascio locale di ossido nitrico, mentre l'inibizione specifica dell'attività di fosfodiesterasi di tipo 5 porta ad aumento del livello di c GMP nei corpi cavernosi. Sotto l'effetto di tadalafil vi è una diminuzione del tono della muscolatura liscia ed aumento del flusso di sangue ai tessuti del pene, che contribuisce a miglioramento dell'erezione. L’azione di tadalafil sulle altre fosfodiesterasi è leggera, pertanto Cialis non ha alcun effetto sul sistema cardiovascolare, sulla funzione del fegato, del muscolo scheletrico e degli altri organi. Tadalafil non modifica le caratteristiche qualitative di spermatozoi, non provoca le variazioni del livello del testosterone, del ormone follicolo-stimolante e luteinizzante nel sangue. L'effetto del farmaco Cialis si sviluppa solo a condizione di stimolazione sessuale. L’inizio dell’effetto terapeutico del tadalafil si verifica 15 minuti dopo la somministrazione. Cialis agisce entro 36 ore dopo la somministrazione orale. If you watch tv, listen to radio, or pay attention to the news, you are familiar with some of the available products that treat erectile dysfunction or impotency in men. Some brands you may recognize are viagra, cialis, and Levitra. Depending on your need or lifestyle, your doctor will determine which medication is the best fit for you. If you wish to have the most flexibility and control for your erection, to ask your doctor about Cialis. Some users refer to Cialis as “the weekend pill” because its effects allow you to achieve an erection any time you want for up to 36 hours following its intake! It may be taken daily when prescribed lower doses, as it also can treat benign prostatic hyperplasia (BPH) and high blood pressure in the lungs. These are just two of the many benefits of name-brand tadalafil.

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