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Adults and children over 12 years: Hypertension: Initially 80mg twice daily, which may be increased at weekly intervals according to response. With concurrent diuretic or other antihypertensive drugs a further reduction of blood pressure is obtained. Angina, migraine and essential tremor: Initially 40mg two or three times daily, increasing by the same amount at weekly intervals according to response. An adequate response in migraine and essential tremor is usually seen in the range 80-160mg daily, and in angina 120-240mg daily. Situational and generalised anxiety: A dose of 40mg daily may provide short term relief of acute situational anxiety. Generalised anxiety, requiring longer term therapy, usually responds adequately to 40mg twice daily which, in individual cases, may be increased to 40mg three times daily. 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